Platforms

Biophysics

Abstract

CONCEPT

The CBQF Structural and Biophysics platform allows to determine several physico-chemical parameters of liquid and semi-solid samples. Indeed, the platform is equipped with an electric scanning microscope for the detailed morphological analysis of sample surfaces. A micro-DSC (differential scanning calorimetry) is a thermoanalytical technique used for retrieving enthalpy of transitions. It is used for a wide array of studies from the determination of the purity of crystalline samples to the study of denaturation of proteins. The platform users may also characterize the size and superficial charge of particles contained in dispersions and solutions, with a Zetasizer Nano ZSP. The equipment contains a high performance system that is especially suited for the characterization of proteins and nanoparticles, offering information regarding mean size, polydispersity index and zeta-potential. Finally, a rheometer can be used in the platform to characterise fluids further than viscosity, through the appliance of force and variation of temperature.

 

OBJECTIVES

The CBQF Structural and Biophysics platform focus on:

Fully characterize the morphology and physico-chemical properties of organic and inorganic samples

To assess the purity of obtained extracts

To represent a crucial part in the product development from different origins, from technological assessment to labelling information

To perform a thorough interpretation of physico-chemical and morphological data to correlate with bioactivity and toxicological issues.

 

CAPACITIES

The CBQF Structural and Biophysics platform is operated by researchers in the biotechnology field and offers the capacity to perform very complete physico-chemical and morphological characterization of samples, with special focus on liquids and semi-solids aimed for human consumption

 

COORDENATION: Maria Manuela Estevez Pintado

Contacts: mpintado@porto.ucp.pt
Tel: 225580000

www.esb.ucp.pt

 

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