Daniela Marlene da Silva Machado

Centre for Biotechnology and Fine Chemistry (CBQF)

Daniela Marlene da Silva Machado


Daniela Machado graduated in Clinical Analysis and Public Health by the Health Technology Superior School of Porto in July 2010. In July of 2017, she obtained PhD degree in Chemical and Biological Engineering at University of Minho through thesis entitled “The prevalence of Gardnerella vaginalis in Portuguese pregnant women and the search for novel alternatives for the treatment of bacterial vaginosis”. From November of 2017 to April 2019, she was researcher fellow in Centre for Biotechnology and Fine Chemistry (CBQF) of the Catholic University of Portugal in a funded FCT project entitled “Tailored microencapsulation technology for beneficial gut extreme oxygen-sensitive bacteria: production, stability and functionality enhancements” (Reference: IF/00588/2015). From May 2019 to present, she is junior researcher in CBQF with funding in scope FCT Stimulus of Scientific Employment Individual Support (Reference: CEECIND/00520/2017) with research plan mainly focused in assessment of therapeutic potential of next generation probiotics in oro-gastrointestinal infections.



Machado D, Almeida D, Seabra CL, Andrade JC, Gomes AM, Freitas AC. Uncovering Akkermansia muciniphila resilience or susceptibility to different temperatures, atmospheres and gastrointestinal conditions. Anaerobe. 2020;61:102135. doi: 10.1016/j.anaerobe.2019.102135.

Almeida D, Machado D, Andrade JC, Mendo S, Gomes AM, Freitas AC. Evolving trends in next-generation probiotics: a 5W1H perspective. Crit Rev Food Sci Nutr. 2020;60(11):1783-1796. doi: 10.1080/10408398.2019.1599812.

Andrade JC, Almeida D, Domingos M, Seabra CL, Machado D, Freitas AC, Gomes AM. Commensal Obligate Anaerobic Bacteria and Health: Production, Storage, and Delivery Strategies. Front Bioeng Biotechnol. 2020;8:550. doi: 10.3389/fbioe.2020.00550.

Machado D, Gaspar C, Palmeira-de-Oliveira A, Cavaleiro C, Salgueiro L, Martinez-de-Oliveira J, Cerca N. Thymbra capitata essential oil as potential therapeutic agent against Gardnerella vaginalis biofilm-related infections. Future Microbiol. 2017;12:407-416. doi: 10.2217/fmb-2016-0184.

Machado D, Castro J, Martinez-de-Oliveira J, Nogueira-Silva C, Cerca N. Prevalence of bacterial vaginosis in Portuguese pregnant women and vaginal colonization by Gardnerella vaginalis. PeerJ. 2017;5:e3750. doi: 10.7717/peerj.3750.

Researcher Center

Centre for Biotechnology and Fine Chemistry (CBQF)


Post Doc

Academic CV