Isabel Sofia Melo Pereira

Centre for Biotechnology and Fine Chemistry (CBQF)

Isabel Sofia Melo Pereira

Isabel Pereira has a Biochemistry graduation (2010), a Bioengineering MSc (2012), a Biomedical Engineering PhD (2019), and a specialization course in Project Management, all at University of Minho. Her PhD work focused on the study of the biocompatibility, safety and effectiveness of a dextrin-based hydrogel, aiming to act as a multifunctional and injectable matrix able to carry and stabilize bone graft granules, stem cells and peptides for bone regeneration. After PhD completion, she went on my work with dextrin HG, aiming to develop new strategies for bone infections treatment, and developed and characterized a self-perforating pH responsive membrane for oral drug delivery. In July 2019, she was hired as PhD Researcher at the CF-UM-UP to developed hydrogels for 3D printing and piezoelectric polymer-based films containing conductive polymers for further tissue engineering applications. Currently, she’s working at Amyris Bio Products Portugal, where she is responsible for genotoxicological assays. Her current research interests are bioactive compounds and functional ingredients for the development of new hygienic, cosmetic and health care products based on circular and sustainable framework economy.




Isabel Pereira; Sónia Fraga; Susana Silva; João Paulo Teixeira; Miguel Gama. "In vitro genotoxicity assessment of an oxidized dextrin-based hydrogel for biomedical applications". Journal of Applied Toxicology 39 4 (2019): 639-649.

Isabel Pereira; Sónia Fraga; Luís Maltez; João Requicha; Luísa Guardão; Joana Oliveira; Justina Prada; et al. "In vivo systemic toxicity assessment of an oxidized dextrin-based hydrogel and its effectiveness as a carrier and stabilizer of granular synthetic bone substitutes". Journal of Biomedical Materials Research Part A (2019):

Isabel Pereira; Joana Simões; Dmitry V. Evtyugin; Sophie Rouif; Manuel A. Coimbra; M. Rosário M. Domingues; Miguel Gama. "Effects of gamma irradiation and periodate oxidation on the structure of dextrin assessed by mass spectrometry". European Polymer Journal 103 (2018): 158-169.

Silva, D.M.; Caseiro, A.R.; Amorim, I.; Pereira, I.; Faria, F.; Pereira, T.; Santos, J.D.; Gama, F.M.; Maurí Cio, A.C.. "Inflammatory response to dextrin-based hydrogel associated with human mesenchymal stem cells, urinary bladder matrix and Bonelike®granules in rat subcutaneous implants". Biomedical Materials (Bristol) 11 6 (2016):

Silva, D.M.; Nunes, C.; Pereira, I.; Moreira, A.S.P.; Domingues, M.R.M.; Coimbra, M.A.; Gama, F.M.. "Structural analysis of dextrins and characterization of dextrin-based biomedical hydrogels". Carbohydrate Polymers 114 (2014): 458-466.

Researcher Center

Centre for Biotechnology and Fine Chemistry (CBQF)

Researcher type

Post Doc

Academic CV