About this research group...

The Biobased and Biomedical Products Research Group has been reorganized to combine CBQF capacity to respond to National and EU priority for future growth of Bioeconomy and Circular Economy, reinforcing capacity and opportunities on the bio-based products. The group focuses on these challenges by exploring novel bioactives and bioproducts from renewable sources (including byproducts), promoting added value applications for food, quality of life and biomedical sectors and using metabolomics approaches to understand biological systems or processes. The group involves a multidisciplinary team to respond to R&I challenges with a wide range of competences. Besides the group receives regularly foreign researchers (ca. 10/year), reflecting the internationalization capacity and consolidated network with academia and industry, with technology transfer of 18 patents.

The group is organized in 3 laboratories:

Group Leader

Freni Tavaria


Bioactives and Bioproducts Research

Biobased and Biomedical Products


Working on integrated solutions to obtain value-added molecules/products from renewable sources, including microalgae, using bio-refinery approach and revealing composition and bioactive and functional properties to define sustainable and high added value applications towards different industrial synergies;


Associate professors

Isabel Braga da Cruz
Rui Manuel Santos Costa de Morais


Adma Nadja Ferreira de Melo
Ezequiel Coscueta
Maria Emilia Brassesco
Adriana Rodrigues Machado
Tânia Isabel Bragança Ribeiro
Sandra Borges
Marta Isabel Correia Coelho

PhD students

Ana Isabel Ribeiro Lopes
Ana Sofia Salsinha
Daniela Oliveira Resende
Helena Rodrigues
Jorge Miguel da Silva Pinto
José Carvalho Soares
Manuela Machado
Maria Teresa Bonifácio Viana Lopes
Marta Sofia de Almeida Mendes
Nadia Silva
Nádia Suati Caetano da Silva
Ricardo Gomez Garcia
Sara Alexandra Dias Marçal
Soudabeh Ghalamara
Daniela da Silva Magalhães
Mariana Correia Pedrosa
Ana Carolina Cassoni
Ana Alexandra Gonçalves Vilas Boas
Cindy Leonor Alves Dias
Diva Alexandra Simões dos Santos Jesus
Valter Filipe Reis Martins
Sara Alexandra dos Santos Cunha
Sofia Sousa
Ricardo Jorge Guedes Paiva Freixo
Marta Fernandez da Cunha

Research Assistants

Dina Isabel Sousa Carvalho das Neves
Filomena Raposa
Joana Patricia Rodrigues Gonçalves
Mariana Sampaio Nogueira
Maria Lima Martingo
Maria Manuel Pereira de Melo Rodrigues


Ricardo Daniel Teixeira Gonçalves
Juliana Isabel Soares Aguiar

Other Collaborators

Silvia Moreira
Ana Paula Soares Martins
Cristina Maria Gonçalves dos Santos
Paulo Filipe Nascimento Costa


Piccirillo C, Rocha C, Tobaldi DM, ullar RC, Labrincha JA, Ferreira MO, Castro PML, Pintado MME. (2014). A hydroxyapatite–Fe2O3 based material of natural origin as an active sunscreen filter. Journal of Materials Chemistry B 2:5999-6009. doi: 10.1039/C4TB00984C

Costa EM, Silva S, Veiga M, Vicente S, Tavaria FK, Pintado ME. (2017). Investigation of chitosan's antibacterial activity against vancomycin resistant microorganisms and their biofilms. Carbohydrates Polymers 174:369-376. doi: 10.1016/j.carbpol.2017.06.087

Madureira AR, Pereira A, Pintado M. (2016). Chitosan nanoparticles loaded with 2,5-dihydroxybenzoic acid and protocatechuic acid: Properties and digestion. Journal of Food Engineering 174:8-14. doi: 10.1016/j.jfoodeng.2015.11.007

Raposo, M. F., Morais, A. M. B., Morais, R. M. S. C. (2016). Emergent Sources of Prebiotics: Seaweeds and Microalgae. Marine Drugs 14(2): E27. doi: 10.3390/md14020027

Yu Y-J, Amorim M, Marques C, Calhau C, Pintado M. (2016). Effects of whey peptide exctract on the growth of probiotics and microbiota. Journal of Functional Foods 21:507-516. doi: 10.1016/j.jff.2015.10.035

Biomaterials and Biomedical technology

Biobased and Biomedical Products


Research on biomaterials and biopolymer engineering for biomedical applications, focusing on wound healing and regeneration and on effective technologies for the terminal sterilization of sensitive biomedical polymers. Investigation of biological properties of biomaterials relevant to the biomedical area.


Assistant professor

Freni Tavaria


Sara Baptista-Silva
Maria Raquel Martins da Costa
João Pedro Bebiano e Costa
Viviana Ribeiro
Cláudia Suellen Ferro de Oliveira

Research Assistant

Francisco Rodrigues
Marta Rosadas
Sara Madureira

MSc students

Joana Fortuna

PhD Students

Anabela Veiga
Beatriz Bernardes
Marta M. Duarte
Andreia Silva Fernandes
Inês Vasconcelos Martins Silva


Duarte MM, Silva VI; Eisenhut, Bionda A, Duarte AR, Oliveira AL, Contributions of Supercritical Fluid Technology for Advancing Decellularization and Postprocessing of Viable Biological Material. Materials Horizons (2021) 2022 Mar 7;9(3):864-891. https://doi.org/10.1039/D1MH01720A.

Veiga A, Magalhães R, Duarte MM, Dias JR, Alves NM, Costa-Pinto AR, Castro F, Rocha F, Oliveira AL. Continuous Production of Highly Tuned Silk/Calcium-Based Composites: Exploring New Pathways for Skin Regeneration. Molecules. 2022 Mar 30;27(7):2249. https://doi.org/10.3390/molecules27072249.

Baptista-Silva S, Borges S, Costa-Pinto AR, Costa R, Amorim M, Dias JR, Ramos Oì, Alves P, Granja PL, Soares R, Pintado M, Oliveira AL. In Situ Forming Silk Sericin-Based Hydrogel: A Novel Wound Healing Biomaterial. ACS Biomaterials Science and Engineering. 2021 (IF 4.152)7, 4; 10.1021/acsbiomaterials.0c01745

Bernardes BG, Del Gaudio P, Alves P, Costa R, García-Gonzaléz CA, Oliveira AL. Bioaerogels: Promising Nanostructured Materials in Fluid Management, Healing and Regeneration of Wounds. Molecules. 2021; 26(13):3834. (IF 3.267) https://doi.org/10.3390/molecules26133834

Lizardo, M., Magalhães, R. M., Tavaria, F. K. (2022). Probiotic Adhesion to Skin Keratinocytes and Underlying Mechanisms. Biology, 11 (9), 1372.https://doi.org/10.3390/biology11091372

Metabolomics & Signal

Biobased and Biomedical Products


Focused on a transversal knowledge detained by CBQF, applied to different biological systems (fermentation, physiological events, etc.) to enable a better understanding of phenomena through signal processing. Several synergies with other internal laboratories have been established to promote CBQF value.


Assistant professor

Pedro Miguel Rodrigues

Senior Researcher

Clara Cecília Santana Sousa

MSc students

Barbara Malafaya
Catarina Rocha
Francisca Monteiro
Ines Barbosa
Joana Soares
Raquel Janeiro
Ricardo Vieira


Castro, C. C.; Martins, R. C.; Teixeira, J. A.; Silva Ferreira, A. C., Application of a high-throughput process analytical technology metabolomics pipeline to Port wine forced ageing process. Food Chemistry 2014, 143 (0), 384-391.

Silva Teixeira, C. S.; Cerqueira, N. M. F. S. A.; Silva Ferreira, A. C., Unravelling the Olfactory Sense: From the Gene to Odor Perception. Chemical Senses 2015.

Monforte, A. R.; Jacobson, D.; Silva Ferreira, A. C., Chemiomics: Network Reconstruction and Kinetics of Port Wine Aging. Journal of Agricultural and Food Chemistry 2015.

Silva Ferreira, A. C.; Monforte, A. R.; Teixeira, C. S.; Martins, R.; Fairbairn, S.; Bauer, F. F., Monitoring Alcoholic Fermentation: An Untargeted Approach. Journal of Agricultural and Food Chemistry 2014, 62 (28), 6784-6793.

Monforte, A. R., Martins, S., & Silva Ferreira, A. C. (2017). Strecker Aldehydes Formation in Wine: New insights of the role of gallic acid, glucose and metals in phenylacetaldehyde formation. Journal of Agricultural and Food Chemistry.