Ana Leite Oliveira

Centre for Biotechnology and Fine Chemistry (CBQF)

Ana Leite Oliveira

Ana Leite Oliveira holds a PhD from the University of Minho (in 2008), collaborating with Depuy Orthopaedics,Inc. (Johnson&Johnson), USA and CSIC, Madrid, followed by a Post-Doc partnering with Tufts University, Boston, USA. She gained expertise in biomaterials for tissue regeneration, working presently in skin-related applications. She has published over 70 international peer reviewed articles and book chapters and participated in more than 100 international scientific and technological conferences, mostly as an oral presenter or as an invited lecturer. The innovation in her work generated 5 patents and links to industry, working with companies to reach new products/processes. She successfully prepared/coordinated various projects funded by National/European agencies and private companies.

Presently she is the head of the Biomaterials and Biomedical Technology Laboratory at CBQF and Invited Assistant Professor at Escola Superior de Biotecnologia, Universidade Católica Portuguesa, responsible for courses in the Master of Biomedical Engineering and Bachelors’ Degree in Bioengineering. Since 2008 she has been assisting the European Commission as an Independent Expert for the Research Executive Agency (REA) in several actions, such as Marie Skłodowska-Curie actions (H2020, FP7), Cost Actions and FET OPEN Calls. Presently, she is Vice-chair for the FET OPEN programme, while also monitoring ongoing FET OPEN projects, in the role of Innovation Radar and as Technical Monitor.



Publications (2016-2020)


Oliveira AL, Silva SB, Borges SC, Alves PJ, Silk Sericin-based Hydrogel, Methods and Uses Thereof, Patent number 20161000045461 (2016); WO/2018/011732 (2018).

San Roman J, Vasquez BM, Garcia LF, Barbosa AM, Gomes F, Oliveira AL, Activators for the crosslinking of polysaccharides and proteins with antioxidant activity, P201730794 (2018).


Papers in international peer-reviewed journals:

Duarte MM, Ribeiro N, Silva IV, Dias JR, Alves NM, Oliveira AL. Fast Decellularization Process Using Supercritical Carbon Dioxide for Trabecular Bone. The Journal of Supercritical Fluids. 2021 Feb 16:105194.

Guimarães I, Baptista-Silva S, Pintado M, Oliveira A.L. Polyphenols: A Promising Avenue in Therapeutic Solutions for Wound Care. Applied Sciences. 2021 Jan;11(3):1230.

Dias J.R., Oliveira da Silva S., Ribeiro N., Batista da Silva Sara, Costa-Pinto A.R., Alves N., Oliveira A.L., In Situ Enabling Approaches For Tissue Regeneration: Current Challenges And New Developments, Frontiers in Bioengineering and Biotechnology, 2020, 8:85 DOI: 10.3389/fbioe.2020.00085.

Veiga A., Castro F., Rocha F, Oliveira A.L. Recent advances in silk sericin/calcium phosphate biomaterials. Frontiers in Materials. 2020; 7:24. doi: 10.3389/fmats.2020.00024.

Ribeiro N., Soares G.C., Santos-Rosales V., Concheiro A., Alvarez-Lorenzo C., García-González C.A. and Oliveira A.L, 2020, A new era for sterilization based on supercritical CO2 technology, Journal of Biomedical Materials Research: Part B - Applied Biomaterials.

Veiga A, Castro F, Reis CC, Sousa A, Oliveira AL, Rocha F. Hydroxyapatite/sericin composites: A simple synthesis route under near-physiological conditions of temperature and pH and preliminary study of the effect of sericin on the biomineralization process. Materials Science and Engineering: C. 2020 Mar 1;108:110400.

Veiga A, Castro F, Rocha F, Oliveira AL. Protein-Based Hydroxyapatite Materials: Tuning Composition toward Biomedical Applications. ACS Applied Bio Materials. 2020, 3, 6, 3441–3455.

Best MG, Cunha-Reis C, Ganin AY, Sousa A, Johnston J, Oliveira AL, Smith DG, Yiu HH, Cooper IR. Antimicrobial Properties of Gallium (III)-and Iron (III)-Loaded Polysaccharides Affecting the Growth of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa, In Vitro. ACS Applied Bio Materials. 2020 Oct 12.

Silva SC, Braz EM, Brito CA, Alves MM, Carvalho FA, Barreto HM, Oliveira AL, Silva DA, Silva-Filho EC. Phthalic anhydride esterified chicha gum: characterization and antibacterial activity. Carbohydrate Polymers. 2020 Sep 13;251:117077.Veiga, Anabela, Filipa Castro, Ana L Oliveira, and Fernando Rocha. "High efficient strategy for the production of hydroxyapatite/silk sericin nanocomposites." Journal of Chemical Technology & Biotechnology (2020). DOI 10.1002/jctb.6532.

Braz EM, Silva SC, Brito CA, Carvalho FA, Alves MM, Barreto HM, Silva DA, Magalhães R, Oliveira AL, Silva-Filho EC. Modified chicha gum by acetylation for antimicrobial and antiparasitic applications: Characterization and biological properties. International Journal of Biological Macromolecules. 2020 May 29.

Santos MV, Oliveira AL, Osajima JA, Silva-Filho EC. Development of composites scaffolds with calcium and cerium-hydroxyapatite and gellan gum. Ceramics International. 2020 Feb 15;46(3):3811-7.

Santos-Rosales V., Ardao I., Alvarez-Lorenzo C., Ribeiro N., Oliveira A.L.*, García-González C.A., Sterile and dual-porous aerogels scaffolds obtained through a multistep supercritical CO2-based approach, Molecules 24.5 (2019): 871.

Ribeiro N., Soares G.C., Santos-Rosales V., Concheiro A., Alvarez-Lorenzo C., García-González C.A. and Oliveira A.L., 2019, A new era for sterilization based on supercritical CO2 technology, Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 2019.

Geão, C., Costa-Pinto, A.R., Cunha-Reis, C., Ribeiro, V.P., Vieira, S., Oliveira, J.M., Reis, R.L. and Oliveira, A.L., 2019. Thermal annealed silk fibroin membranes for periodontal guided tissue regeneration. Journal of Materials Science: Materials in Medicine, 30(2), p.27.

Serôdio R., Schickert S.L., Costa-Pinto A.R., Dias J.R., Granja P.L., Yang F., and Oliveira A.L., 2019. Ultrasound sonication prior to electrospinning tailors silk fibroin/PEO membranes for periodontal regeneration. Materials Science and Engineering: C. Volume 98, May 2019, p. 969-981.

Soares G.C., Learmonth D.A., Vallejo M.C., Davila S.P., González P., Sousa R.A. and Oliveira A.L., 2019. Supercritical CO2 technology: The next standard sterilization technique?. Materials Science and Engineering: C, Volume 99, June 2019, p. 520-540.

Ribeiro V., Pina S., Costa J.B., Cengiz I.F., García-Fernández L., Fernández-Gutiérrez M.D.M., Paiva O.C., Oliveira A.L., San Roman, J., Oliveira, J.M. and Reis, R.L., 2019. Enzymatically crosslinked silk fibroin-based hierarchical scaffolds for osteochondral regeneration. ACS applied materials & interfaces. 2019, 11 (4), pp 3781–3799. DOI: 10.1021/acsami.8b21259.

Dias J.R., Baptista-Silva S., Sousa A., Oliveira A.L., Bártolo P.J. and Granja P.L., 2018. Biomechanical performance of hybrid electrospun structures for skin regeneration. Materials Science and Engineering: C, 93, pp.816-827.

Ribeiro V.P., da Silva Morais A., Maia F.R., Canadas R.F., Costa J.B. Oliveira, A.L., Oliveira J.M. and Reis, R.L., 2018. Combinatory approach for developing silk fibroin scaffolds for cartilage regeneration. Acta biomaterialia, 72, pp.167-181.doi:10.1016/j.actbio.201.03.047, 2018.

Ribeiro V. P., Silva-Correia J., Gonçalves C., Pina S., Radhouani H., Hyttinen J., Roy A., Oliveira A.L., Reis R. L., and Oliveira J. M., Rapidly responsive silk fibroin hydrogels as an artificial matrix for the programmed tumor cells death, PLoS ONE, vol. 13, issue 4, pp. e0194441, doi:10.1371/journal.pone.0194441, 2018.

Dias, J.R., Baptista-Silva, S., de Oliveira, C.M.T., Sousa, A., Oliveira A.L., Bártolo P.J. and Granja, P.L., 2017. In situ crosslinked electrospun gelatin nanofibers for skin regeneration. European Polymer Journal, 95, pp.161-173.

Ribeiro VP, Silva-Correia J, Nascimento AI, daSilva Morais A, Marques AP, Ribeiro AS, Silva C, Bonifácio G, Sousa RA, Oliveira JM, Oliveira AL, Reis RL, Complex 3D Biotextiles for Flat BoneTissue Engineering Applications, Biomaterials, Biomaterials, Volume 123, April 2017, Pages 92–106. IF: 8.978.

Yan L. P., Silva-Correia J., Ribeiro, V.P., Miranda-Gonçalves V., Correia C., Silva Morais A., Sousa, R.A., Reis R. M., Oliveira AL, Oliveira J. M. and Reis R. L., Tumor Growth Suppression Induced by Biomimetic Silk Fibroin Hydrogels, Scientific Reports, vol. 6, issue 31037, doi:10.1038/srep31037, 2016. IF: 5.228

Le-Ping Y., Oliveira J.M., Oliveira A.L., and Reis R. L., "Core-shell Silk Hydrogels with Spatially Tuned Conformations as Drug Delivery System", Journal of Tissue Engineering and Regenerative Medicine, doi:TERM-16-0043.R1, 2016.

Castro F, Ribeiro VP, Ferreira A, Oliveira AL, Reis RL, Teixeira JA and Rocha F, Continuous-flow precipitation as a route to prepare highly controlled nanohydroxyapatite: in vitro mineralization and biological evaluation, Materials Research Express, vol. 3, issue 7, doi:10.1088/2053-1591/3/7/075404, 2016.

Ribeiro VP, Almeida, Martins AR, Pashkuleva I., Marques A.P., Ribeiro A.S., Silva C.J., Bonifácio G., Sousa, R.A., Oliveira AL, Reis RL, Modulating Cell Adhesion to Polybutylene Succinate Biotextile Constructs for Tissue Engineering Applications, Tissue Engineering and Regenerative Medicine, DOI: 10.1002/term.2189, 2016.

Researcher Center

Centre for Biotechnology and Fine Chemistry (CBQF)

Academic CV